Recombinant Human S100A8&S100A9 Heterodimer Protein (His Tag)
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- 表达系统: E.coli
- 蛋白编码: P05109&P06702
别称 |
S100A8/S100A9 Heterodimer
|
表达系统 |
E.coli
|
序列 |
Met 1-Glu93(S100A8)&Thr 2-Pro114(S100A9)
|
蛋白编码 |
P05109&P06702
|
种属 |
Human
|
计算分子量 |
11.7&13.2 kDa
|
表观分子量 |
13&15 kDa
|
标签 |
C-His
|
纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
|
运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
制剂 |
Supplied as a 0.2 μm filtered solution of 20mM HEPES, 10% Glycerol, 150mM NaCl, 2.5mM EDTA, pH 7.4.
|
复溶方法 |
Not Applicable
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背景 |
S100A8 is a member of the S100 family, EF-hand superfamily of Ca-binding proteins. It is produced by neutrophils and monocytes, and forms Ca2+-dependent heterodimer/heterotetramer complexes (termed calprotectin) with S100A9. Calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase.
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实验操作视频
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