Recombinant Human S100B Protein (His Tag)
Price:
Size:
50μg
10μg
- 表达系统: E.coli
- 蛋白编码: P04271
别称 |
Protein S100-B;S-100 protein beta chain;S-100 protein subunit beta;S100 calcium-binding protein B;S100b;S100 beta;S100 calcium binding protein B;NEF;S100;S100-B;S100beta
|
表达系统 |
E.coli
|
序列 |
Met 1-Glu92
|
蛋白编码 |
P04271
|
种属 |
Human
|
计算分子量 |
12.2 kDa
|
表观分子量 |
12 kDa
|
标签 |
N-His
|
纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
|
制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
复溶方法 |
Please refer to the printed manual for detailed information.
|
背景 |
S100-B; is an acidic protein with a molecular weight of 21 kDa belonging to the S100 family. S100-B contains two EF-hand-type calcium-binding motifs separated by a hinge region with a hydrophobic cleft. S100-B plays an important role in neurodevelopment; differentiation; and brain construction. S100-B has neuroprotective effects; but at high concentrations S100-B is neurotoxic. Extracellular concentration of S100-B increases following brain damage; which easily penetrates into cerebrospinal fluid in brain damage and then into the blood. S100-B is expressed and produced by astrocytes in vertebrate brains and in the CNS; and the astrocytes are the major cells producing S100-B protein in gray matter; as well as oligodendrocytes are the predominant S100-B in protein producing cells in white matter. The major advantage of using S100-B is that elevations in serum or CSF levels provide a sensitive measure for determining CNS injury at the molecular level before gross changes develop; enabling timely delivery of crucial medical intervention before irreversible damage occurs. In addition; S100-B; which is also present in human melanocytes; is a reliable marker for melanoma malignancy both in bioptic tissue and in serum.
|
实验操作视频
新品推荐
Recombinant Human IL-6 Protein (Fc Tag)
Recombinant Mouse BCR protein (His tag)
Recombinant Mouse IL6 protein(His tag)
Recombinant Rat IL2/IL-2/Interleukin-2 protein (His tag)
Recombinant SARS-CoV-2 Nucleocapsid Protein (His Tag)
Recombinant Human Fyn protein(His tag)
Recombinant Mouse CD96/TACTILE protein (His tag)