Recombinant Human SENP7 Protein
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- 表达系统： E.coli
- 蛋白编码： Q9BQF6
| 别称 |
Sentrin-Specific Protease 7;SUMO-1-Specific Protease 2;Sentrin/SUMO-Specific Protease SENP7;SENP7;KIAA1707;SSP2;SUSP2
|
| 表达系统 |
E.coli
|
| 序列 |
Met695-Ala864
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| 蛋白编码 |
Q9BQF6
|
| 种属 |
Human
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| 计算分子量 |
19.8 kDa
|
| 表观分子量 |
22 kDa
|
| 标签 |
None
|
| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
|
| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM HEPES, 5% Glycerol, pH 7.4.
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| 复溶方法 |
Not Applicable
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| 背景 |
Sentrin-Specific Protease 7 (SENP7) acts as a SUMO-2/3-specific protease. SENP7 is likely to regulate the metabolism of poly-SUMO-2/3 rather than SUMO-1 conjugation in vivo. SENP7 has a restricted substrate specificity, and displaying paralogue-specific isopeptidase activity. The C-terminal catalytic domain of SENP7 depolymerized poly-SUMO-2 chains but does not have activity against poly-SUMO-1 chains. SENP7 also had isopeptidase activity against di-SUMO-2- and SUMO-2-modified RanGAP1 (Ran GTPase-activating protein 1) but had limited activity against SUMO-1-modified RanGAP1.
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实验操作视频
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