Recombinant Human UBE2D1 Protein (GST Tag)
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- 表达系统: E.coli
- 蛋白编码: P51668
别称 |
Ubiquitin-conjugating enzyme E2 D1;Stimulator of Fe transport;SFT;UBC4/5 homolog;UbcH5;Ubiquitin carrier protein D1;Ubiquitin-conjugating enzyme E2(17)KB 1;Ubiquitin-conjugating enzyme E2-17 kDa 1;Ubiquitin-protein ligase D1;SFT;UBC5A;UBCH5;UBCH5A
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表达系统 |
E.coli
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序列 |
Met 1-Met 147
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蛋白编码 |
P51668
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种属 |
Human
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计算分子量 |
42.9 kDa
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表观分子量 |
40 kDa
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标签 |
N-GST
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纯度 |
> 95 % as determined by reducing SDS-PAGE.
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内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
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制剂 |
Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5.
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复溶方法 |
Not Applicable
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背景 |
Ubiquitin-conjugating enzyme E2 D1(UBE2D1)belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes; or E1s; ubiquitin-conjugating enzymes; or E2s; and ubiquitin-protein ligases; or E3s. This enzyme is closely related to a stimulator of iron transport (SFT); and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.
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实验操作视频
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