Recombinant Mouse 4-1BB/TNFRSF9 Protein (aa 24-187, Fc Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： P20334
| 别称 |
4-1BB;A930040I11Rik;AA408498;AI325004;Cd137;CDw137;ILA;Ly63;Secreted CD137 antigen;Tumor necrosis factor receptor superfamily member 9;Tnfrsf9
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| 表达系统 |
HEK293 Cells
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| 序列 |
Val24-Leu187
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| 蛋白编码 |
P20334
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| 种属 |
Mouse
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| 计算分子量 |
44.7 kDa
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| 表观分子量 |
60-70 kDa
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| 标签 |
C-Fc
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
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| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
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| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
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| 复溶方法 |
Not Applicable
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| 背景 |
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.
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实验操作视频
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