Recombinant Mouse CD38 Protein (His Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： P56528
| 别称 |
cADPr hydrolase 1;CD38 antigen (p45);CD38 antigen;CD38 molecule;CD38;Cyclic ADP-ribose hydrolase 1;Cyclic ADP-ribose Hydrolase;EC 3.2.2.5;NAD(+) nucleosidase;T10;;ADPRC 1-rs1;ADPRC1;Cd38;Cd38-rs1;I-19
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| 表达系统 |
HEK293 Cells
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| 序列 |
Leu45-Thr304
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| 蛋白编码 |
P56528
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| 种属 |
Mouse
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| 计算分子量 |
30.6 kDa
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| 表观分子量 |
38-47 kDa
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| 标签 |
C-His
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
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| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
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| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
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| 复溶方法 |
Not Applicable
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| 背景 |
CD38, also known as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, is a Signal-anchor for type II membrane protein. CD38 is able to transform NAD+ to ADP-D-ribose and nicotinamide. It also can transform NADP+ to nicotinate-adenine dinucleotide phosphate and nicotinamide. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
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实验操作视频
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