Recombinant Mouse Galectin 9/LGALS9 Protein (GST Tag)
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- 表达系统: E.coli
- 蛋白编码: O08573-2
别称 |
Galectin-9;Lgals9;Gal-9
|
表达系统 |
E.coli
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序列 |
Met1-Thr322
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蛋白编码 |
O08573-2
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种属 |
Mouse
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计算分子量 |
62.8 kDa
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表观分子量 |
58 kDa
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标签 |
N-GST
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纯度 |
> 85 % as determined by reducing SDS-PAGE.
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内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
|
运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
制剂 |
Supplied as a 0.2 μm filtered solution of 20mM PB, 1mM EDTA, 5mM β-Mercaptoethanol, 5% Trehalose, 400mM NaCl, pH6.5.
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复溶方法 |
Not Applicable
|
背景 |
Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1.
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实验操作视频
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