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Recombinant Mouse Granzyme B(G,H)/GZMB Protein (His Tag)

Price: ¥5328 ¥1784

Size:
50μg 10μg
  • 表达系统: HEK293 Cells
  • 蛋白编码: P04187
别称
Granzyme B(G,H);CTLA-1;Cytotoxic cell protease 1;CCP1;Fragmentin-2;Gzmb;Ctla-1;Ctla1
表达系统
HEK293 Cells
序列
Gly19-Ser247
蛋白编码
P04187
种属
Mouse
计算分子量
26.5 kDa
表观分子量
35 kDa
标签
C-His
纯度
> 95 % as determined by reducing SDS-PAGE.
内毒素
< 1.0 EU per μg of the protein as determined by the LAL method.
保存条件
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
运输条件
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
制剂
Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
复溶方法
Not Applicable
背景
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.


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