Recombinant Mouse Granzyme B(G,H)/GZMB Protein (His Tag)
Price:
- 表达系统: HEK293 Cells
- 蛋白编码: P04187
别称 |
Granzyme B(G,H);CTLA-1;Cytotoxic cell protease 1;CCP1;Fragmentin-2;Gzmb;Ctla-1;Ctla1
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表达系统 |
HEK293 Cells
|
序列 |
Gly19-Ser247
|
蛋白编码 |
P04187
|
种属 |
Mouse
|
计算分子量 |
26.5 kDa
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表观分子量 |
35 kDa
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标签 |
C-His
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纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
|
运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
制剂 |
Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
|
复溶方法 |
Not Applicable
|
背景 |
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
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实验操作视频
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