CST3 Polyclonal Antibody

Verified Samples in WB:Human Hep G2,Human PC-3,Human Caco-2,Mouse Kidney,Rat Kidney
Verified Samples in IHC:Human kidney,Mouse kidney

WB:1:500-1:1000, IHC 1:250-1:500

Polyclonal

IgG

Recombinant Human CST3 protein expressed by E.coli

CST3

AD8; Amyloid angiopathy and cerebral hemorrhage; ARMD11; CST3 protein; Cystatin 3; CystatinC; Epididymis secretory protein Li 2; bA218C14.4; Gamma trace; HCCAA; HEL S 2; Neuroendocrine basic polypeptide; Post gamma globulin

15 kDa

15 kDa

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide, 50% glycerol, pH 7.4

Affinity purification

Tags and Cell markers; Cell Biology; Stem Cells; Cardiovascular

Unconjugated

Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration,shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions,establishing its role in vascular disease. In addition,this protein has been shown to have an antimicrobial function,inhibiting the replication of herpes simplex virus.