Galectin 3 Polyclonal Antibody

Verified Samples in WB:Human MCF-7,Mouse NIH/3T3,Mouse Raw264.7
Verified Samples in IHC:Human colon cancer,Human stomach cancer

WB 1:500-1:2000, IHC 1:150-1:300

Polyclonal

IgG

Recombinant Human LGALS3 protein expressed by E.coli

Galectin

35 kDa lectin;Carbohydrate binding protein 35;Carbohydrate-binding protein 35;CBP 35;CBP35;Gal-3;GAL3;Galactose-specific lectin 3;Galactoside-binding protein;GALBP;Galectin 3 internal gene;included;Galectin-3;Galectin3;GALIG;GBP;IgE binding protein;IgE-binding protein;L 31;L 34;L-31;L-34 galactoside-binding lectin;L31;Laminin-binding protein;Lectin L-29;Lectin;galactose binding;soluble 3;LEG3;LGALS2;LGALS3;MAC 2 antigen;Mac-2;Mac-2 antigen;MAC2;Macrophage galactose-specific lectin;MGC105387

26 kDa

26 kDa

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide, 50% glycerol, pH 7.4

Affinity purification

Cell Biology; Epigenetics and Nuclear Signaling; Stem Cells; Cancer

Unconjugated

Galectins are a family of animal lectins defined by shared characteristic amino-acid sequences and affinity for β-galactose-containing oligosac-charides . Galectin-3 contains one carbohydrate recognition domain (CRD) and a proline- and glycine-rich N-terminal domain through which is able to form oligomers. Galectin-3 is widely expressed in many normal tissues and a variety of tumors. It is found intracellularly in nucleus and cytoplasm or secreted outside of cell,being present on the cell surface or in the extracellular space . Galectin-3 is involved in various biological processes including cell growth,adhesion,differentiation,apoptosis,angiogenesis,immune response,neoplastic transformation and metastasis .