PI Reagent (50μg/mL)
中文名称:碘化丙啶(PI)染色液

Price:
检测原理 | 碘化丙啶(Propidium Iodide,PI)是一种核酸染料,由于死细胞的细胞膜选择透过性丧失,PI可以进入胞内与双链DNA特异性结合并产生强烈的红色荧光 (Ex/Em=535nm/617nm),从而对死细胞进行标记。PI不能透过完整的细胞膜,但能够透过死细胞和凋亡中晚期细胞的细胞膜而使细胞核红染,因此,作为荧光探针常用于细胞凋亡或细胞坏死的检测。在流式细胞和激光共聚焦分析中,常用于凋亡早晚期的细胞以及死细胞的区分以及在免疫染色时用于死细胞的非特异性染色的减除。由于PI可以定量插入DNA中,因此,还可用于细胞周期的分析与测定研究。 |
保存温度 | 该产品可在 2~8°C避光条件下保存12个月。 |
有效期 | 12个月 |
运输条件 | 冰袋 |
-
Proximal tubular FHL2, a novel downstream target of hypoxia inducible factor 1, is a protector against ischemic acute kidney injury
IF: 6.200Journal: CELLULAR AND MOLECULAR LIFE SCIENCES (2024) -
Serum deprivation protein response intervenes in the proliferation, motility, and extracellular matrix production in keloid fibroblasts by blocking the amplification of TGF-β1/SMAD signal cascade via ERK1/2
IF: 3.300Journal: TOXICOLOGY AND APPLIED PHARMACOLOGY (2024) -
Hyperactivation of p53 contributes to mitotic catastrophe in podocytes through regulation of the Wee1/CDK1/cyclin B1 axis
IF: 3.000Journal: RENAL FAILURE (2024) -
p110CUX1 promotes acute myeloid leukemia progression via regulating pyridoxal phosphatase expression and activating PI3K/AKT/mTOR signaling pathway
IF: 3.000Journal: MOLECULAR CARCINOGENESIS (2024)DOI:10.1002/mc.23793 -
miR-16-5p regulates aerobic glycolysis and tumorigenesis of NSCLC cells via LDH-A/lactate/NF-κB signaling
IF: 6.780 -
PP2Acα promotes macrophage accumulation and activation to exacerbate tubular cell death and kidney fibrosis through activating Rap1 and TNFα production
IF: 15.828Journal: CELL DEATH AND DIFFERENTIATION (2021)PMID:33934104Reactivity:MouseSample Type:Cell sample -
The deubiquitinase USP10 restores PTEN activity and inhibits non–small cell lung cancer cell proliferation
IF: 5.157 -
PRUNE2 inhibits progression of colorectal cancer in?vitro and in?vivo
IF: 2.447