S100B Polyclonal Antibody
Price:
Size:
100μL
50μL
- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: WB;IHC
Verified Samples |
Verified Samples in WB:Rat brain Verified Samples in IHC:Rat brain,Mouse brain |
Dilution | WB:1:500-1:1000,IHC 1:200-1:500 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant Human S100B protein expressed by E.coli |
Abbre | S100B |
Synonyms | NEF;Protein S100 B;Protein S100-B;S 100 calcium binding protein beta chain;S 100 protein beta chain;S-100 protein beta chain;S-100 protein subunit beta;S100;S100 calcium binding protein beta (neural);S100 calcium-binding protein B;S100 protein beta chain;S100B;S100B_HUMAN;S100beta |
Swissprot | |
Calculated MW | 10kDa |
Observed MW | 10kDa |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH 7.4 |
Purification Method | Affinity purification |
Research Areas | Cell Biology;Epigenetics and Nuclear Signaling;Stem Cells |
Conjugation | Unconjugated |
Background | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. |
Western blot with anti-S100B polyclonal Antibody at dilution of 1:500.lane 1: Rat brain tissue
Immunohistochemistry of paraffin-embedded Rat brain using S100B Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Mouse brain using S100B Polyclonal Antibody at dilution of 1:500
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |