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S100B Polyclonal Antibody

S100B Polyclonal Antibody
  • S100B Polyclonal Antibody
  • S100B Polyclonal Antibody
  • S100B Polyclonal Antibody
  • S100B Polyclonal Antibody

Price: ¥2100.00 ¥800.00

Size:
100 μL 25 μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB: Rat brain
Verified Samples in IHC: Rat brain, Mouse brain
Dilution
WB 1:500-1:1000, IHC 1:200-1:500
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant Human S100B protein expressed by E.coli
Abbre
S100B
Synonyms
NEF, Protein S100 B, Protein S100-B, S 100 calcium binding protein beta chain, S 100 protein beta chain, S-100 protein beta chain, S-100 protein subunit beta, S100, S100 calcium binding protein beta (neural), S100 calcium-binding protein B, S100 protein beta chain
Swissprot
Calculated MW
10 kDa
Observed MW
10 kDa
Concentration
1 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4
Purification Method
Antigen Affinity Purification
Research Areas
Cell Biology, Epigenetics and Nuclear Signaling, Stem Cells
Conjugation
Unconjugated
Background
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
Western blot with anti-S100B polyclonal Antibody at dilution of 1:500.lane 1: Rat brain tissue
Immunohistochemistry of paraffin-embedded Rat brain using S100B Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Mouse brain using S100B Polyclonal Antibody at dilution of 1:500


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