AFP Polyclonal Antibody
Price:
Size:
100μL
50μL
- 宿主: Rabbit
- 反应性: Human
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human liver cancer |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant Human AEP protein expressed by E.coli |
Abbre | AFP |
Synonyms | Alpha-fetoprotein;Alpha-fetoglobulin;AFP;HPAFP |
Swissprot | |
Concentration | 1mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide,50% glycerol pH 7.4 |
Purification Method | Antigen Affinity Purification |
Research Areas | Cancer;Cardiovascular;Developmental Biology |
Conjugation | Unconjugated |
Background | Alpha-fetoprotein (AFP) is classified as a member of the albuminoid gene superfamily consisting of albumin,AFP,vitamin D (Gc) protein,and alpha-albumin. AFP is a glycoprotein of 591 amino acids and a carbohydrate moiety. AFP is one of the several embryo-specific proteins and is a dominant serum protein as early in human embryonic life as one month,when albumin and transferrin are present in relatively small amounts. It is first synthesized in the human by the yolk sac and liver(1-2 months) and subsequently predominantly in the liver. A small amount of AFP is produced by the GI tract of the human conceptus. It has been proved that AFP may reappear in the serum in elevated amounts in adult life in association with normal restorative processes and with malignant growth. Alpha-fetoprotein (AFP) is a specific marker for hepatocellular carcinoma (HCC),teratoblastomas,and neural tube defect (NTD). |
Immunohistochemistry of paraffin-embedded Human liver cancer using AFP Polyclonal Antibody at dilution of 1:600
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