ALKBH2 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human;Mouse
- 应用性： WB
| Verified Samples |
Verified Samples in WB:Human fetal liver,Human seminoma,RAW264.7 |
| Dilution | WB 1:500-1:2000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein of human ALKBH2 |
| Abbre | ALKBH2 |
| Synonyms | 2OG Fe(II) oxy DC1;9530023G02;ABH 2;ABH2;alkB alkylation repair homolog 2;ALKB2;ALKBH2 alkB;ALKBH2;Alkylated DNA repair protein alkB homolog;Alkylated DNA repair protein alkB homolog 2;Alkylation repair homolog 2;Alpha ketoglutarate dependent dioxygenase alkB homolog 2;Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2;AU016977;DNA oxidative demethylase ALKBH2;EC 1.14.11.;FLJ99103;hABH2;mABH2;MGC90512;Oxy DC1抗体 |
| Swissprot | |
| Calculated MW | 29kDa |
| Cellular Localization | Nucleus. Detected in replication foci during S-phase. |
| Concentration | 0.3 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Background | The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron. |
Western Blot analysis of Human fetal liver and seminoma tissue, RAW264.7 cell using ALKBH2 Polyclonal Antibody at dilution of 1:800
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
