BAD Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human colon,Human stomach cancer,Mouse lung,Rat spleen |
Dilution | IHC 1:300 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Bad |
Abbre | BAD |
Synonyms | AI325008;BAD;BAD;BBC 2;BBC2;BBC6;Bcl 2 Antagonist of Cell Death;Bcl 2 Binding Component 6;BCL X / BCL 2 Binding Protein;BCL X Binding Protein;Bcl XL/Bcl 2 Associated Death Promoter;Bcl-2-binding component 6;Bcl-2-like protein 8;Bcl-XL/Bcl-2-associated death promoter;Bcl2 antagonist of cell death;BCL2 antagonist of cell death protein;BCL2 associated agonist of cell death;Bcl2 Associated Death Promoter;BCL2 binding component 6;BCL2 binding protein;Bcl2 Like 8 Protein;Bcl2-L-8;BCL2L8;Proapoptotic BH3 Only Protein抗体 |
Swissprot | |
Cellular Localization | Mitochondrion outer membrane. Cytoplasm. Upon phosphorylation, locates to the cytoplasm. |
Concentration | 300 μg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Cell Biology; Metabolism |
Conjugation | Unconjugated |
Background | The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. |
Immunohistochemistry analysis of paraffin-embedded human colon using BAD Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded human stomach cancer using BAD Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded mouse lung using BAD Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat spleen using BAD Polyclonal Antibody at dilution of 1:300.
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |