C3 Polyclonal Antibody
Price:
Size:
100μL
50μL
- 宿主: Rabbit
- 反应性: Mouse
- 应用性: WB
Verified Samples |
Verified Samples in WB:Mouse serum |
Dilution | WB 1:500-1:1000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant Mouse C3 Protein expressed by E.coli |
Abbre | C3 |
Synonyms | Complement C3;HSE-MSF;C3 |
Swissprot | |
Calculated MW | 19kDa |
Observed MW | 15kDa |
Concentration | 1mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide,50% glycerol pH 7.4 |
Purification Method | Antigen Affinity Purification |
Conjugation | Unconjugated |
Background | C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently,via its reactive thioester,to cell surface carbohydrates or immune aggregates.
Derived from proteolytic degradation of complement C3,C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation,acts as a chemoattractant for neutrophils.It induces the contraction of smooth muscle,increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. The short isoform has B-cell stimulatory activity. |
Western blot with C3 Polyclonal antibody at dilution of 1:1000.lane 1: Mouse serum
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E-IR-R304A | Western Blot Detection Kit | 50Assays |
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