CBFA2T2 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human; Mouse
- 应用性： WB
| Verified Samples |
Verified Samples in WB:293T,Raji,Jurkat,HepG2 |
| Dilution | WB 1:1000-1:5000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Fusion protein of human CBFA2T2 |
| Abbre | CBFA2T2 |
| Synonyms | AML1 MTG8;cbfa2t2;Core binding factor runt domain alpha subunit 2 translocated to 2;core-binding factor; runt domain; alpha subunit 2;DKFZp313F2116;EHT;ETO homolog on chromosome 20;ETO homologous on chromosome 20;MTG 8 like protein;MTG 8 related protein 1;MTG8 like protein;MTG8 related protein 1;MTG8-like protein;MTG8-related protein 1;MTG8R;MTGR 1;Myeloid translocation gene related protein 1;Myeloid translocation related protein 1;Myeloid translocation-related protein 1;p85;Protein CBFA2T2;ZMYND 3;ZMYND3抗体 |
| Swissprot | |
| Calculated MW | 67 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Nucleus. |
| Concentration | 1.26 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Tags;Cell Markers |
| Conjugation | Unconjugated |
| Background | In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described. |
Western blot analysis of 293T Raji Jurkat HepG2 cell lysates using CBFA2T2 Polyclonal Antibody at dilution of 1:1000
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
