CBX5 Monoclonal Antibody
Price:
Size:
120μL
60μL
20μL
- 宿主： Mouse
- 反应性： Human;Mouse;Rat
- 应用性： WB;IHC-p
| Verified Samples |
Verified Samples in WB:Hela,3T3,PC12 Verified Samples in IF:Human uterus,Human uterus |
| Dilution | WB 1:500-2000;IHC 1:50-300 |
| Clonality | Monoclonal |
| Isotype | IgG |
| Immunogen | Recombinant Protein of HP-1α |
| Abbre | CBX5 |
| Synonyms | Antigen p25;CBX5;CBX5;CG8409;Chromobox 5;Chromobox homolog 5 (HP1 alpha homolog;Drosophila);Chromobox homolog 5;Chromobox protein homolog 5;Epididymis luminal protein 25;HEL25;Heterochromatin protein 1 alpha;Heterochromatin protein 1;Heterochromatin protein 1 homolog alpha;HP1 alpha;HP1 alpha homolog;HP1;HP1A;HP1Hs alpha;Su(var)205 |
| Swissprot | |
| Observed MW | 22kDa |
| Cellular Localization | Nucleus. Chromosome. Chromosome>centromere. Component of centromeric and pericentromeric heterochromatin. Associates with chromosomes during mitosis. Associates specifically with chromatin during metaphase and anaphase. |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
| Purification Method | Protein A purification |
| Research Areas | Cancer; Epigenetics and Nuclear Signaling; Tags and Cell Markers |
| Clone No. | 7B6 |
| Conjugation | Unconjugated |
| Background | This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Western Blot analysis of 1) Hela, 2)3T3, 3) PC-12 cells using CBX5 Monoclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human uterus tissue using CBX5 Monoclonal Antibody at dilution of 1:200.
Immunofluorescence analysis of Human uterus tissue using CBX5 Monoclonal Antibody at dilution of 1:200.
| E-AB-1001 | Goat Anti-Mouse IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1024 | Goat Anti-Mouse IgG(H+L)(Biotin conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1196 | HRP-Goat Anti-Mouse IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
