CD45 Monoclonal Antibody
Price:
Size:
120μL
60μL
20μL
- 宿主: Mouse
- 反应性: Human
- 应用性: WB;IHC-p
Verified Samples |
Verified Samples in WB:Hela Verified Samples in IHC:Human lung cancer Verified Samples in IF:Human liver cancer |
Dilution | WB 1:500-1:2000;IHC 1:50-300 |
Clonality | Monoclonal |
Isotype | IgG |
Immunogen | Synthetic Peptide |
Abbre | CD45 |
Synonyms | B220;CD 45;CD45;CD45 antigen;CD45R;GP180;L-CA;LCA;Leukocyte common antigen;loc;Ly-5;LY5;Ly5;homolog of;Lyt-4;OTTHUMP00000033813;OTTHUMP00000033816;OTTHUMP00000033817;OTTHUMP00000038574;Protein tyrosine phosphatase receptor type c polypeptide;Protein tyrosine phosphatase;receptor type C;protein tyrosine phosphatase;receptor type;C;Protein tyrosine phosphatase;receptor type;c polypeptide;Ptprc;PTPRC;Receptor-type tyrosine-protein phosphatase C;T200;T200 glycoprotein;T200 leukocyte common antigen抗体 |
Swissprot | |
Calculated MW | 147kDa |
Observed MW | 147kDa |
Cellular Localization | Membrane |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method | Protein A purification |
Research Areas | Cancer; Cardiovascular; Immunology; Neuroscience; Signal Transduction; Stem Cells |
Clone No. | Clone:3H3 |
Conjugation | Unconjugated |
Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. |
Western Blot analysis of Hela cells using CD45 Monoclonal Antibody at dilution of 1:2000.
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using CD45 Monoclonal Antibody at dilution of 1:200.
Immunofluorescence analysis of Human liver cancer tissue using CD45 Monoclonal Antibody at dilution of 1:200.
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