CD68 Monoclonal Antibody

Verified Samples in IHC:Human tonsil,Human tonsil
Verified Samples in IF:Human lung cancer

IHC 1:100-1:300, IF 1:50-200

Monoclonal

IgG

Synthetic Peptide

CD68

CD 68;CD68;CD68 antigen;CD68 molecule;CD68;DKFZp686M18236;gp11;Gp110;LAMP4;Macrophage antigen CD68 (microsialin);MACROPHAGE ANTIGEN CD68;Macrosialin;SCARD1;Scavenger receptor class D member 1抗体

Membrane

Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites.

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Protein A purification

Cancer; Immunology

Clone:2K6

Unconjugated

CD68 is a type I transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It belongs to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. CD68 is also a member of the scavenger receptor family. It may play a role in phagocytic activities of tissue macrophages.