CD74 Polyclonal Antibody

Verified Samples in WB:Raji
Verified Samples in IHC:Human tonsil,Human lung cancer,Mouse spleen,Rat spleen

WB 1:500-1:1000 , IHC 1:100-1:300

Polyclonal

IgG

Recombinant Human HLA class II histocompatibility antigen gamma chain protein

CD74

CD 74;CD74;CD74 antigen (invariant polypeptide of major histocompatibility complex;class II antigen-associated);CD74 antigen;CD74 molecule;CD74 molecule;major histocompatibility complex;class II invariant chain;CLIP;DHLAG;Gamma chain of class II antigens;HG2A;HLA class II histocompatibility antigen gamma chain;HLA DR antigens associated invariant chain;HLA DR gamma;HLA-DR antigens-associated invariant chain;HLA-DR-gamma;HLADG;HLADR antigens associated invariant chain;Ia antigen associated invariant chain;Ia antigen-associated invariant chain;Ia associated invariant chain;Ia gamma;Ii;Invariant polypeptide of major histocompatibility complex class II antigen associated;la-gamma;Major histocompatibility complex class II invariant chain;MHC HLA DR gamma chain;MHC HLA-DR gamma chain;p33;p35;Protein 41抗体

33,26,18 kDa

35 kDa

Cell membrane, Endoplasmic reticulum, Endosome, Golgi apparatus, Lysosome, Membrane

0.95 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Antigen Affinity Purification

Cancer; Immunology

Unconjugated

The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.