CHI3L1 Polyclonal Antibody

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- 宿主: Rabbit
- 反应性: Mouse
- 应用性: WB
Verified Samples |
Verified Samples in WB: Mouse spleen, Mouse lung |
Dilution | WB 1:500-1:1000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant Mouse CHI3L1 protein expressed by E.coli |
Abbre | CHI3L1 |
Synonyms | Cartilage glycoprotein 39 (CGP-39, BRP39 protein, Breast regression protein 39, Brp39, Chi3l1, Chil1, Chitinase-3-like protein 1, GP-39), YKL40 |
Swissprot | |
Calculated MW | 44 kDa |
Observed MW | 43 kDa |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
Purification Method | Antigen Affinity Purification |
Conjugation | Unconjugated |
Background | Chitinase-3-like protein 1 (CHI3L1) also known as YKL-40,is a .secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 gene. Elevated levels of CHI3L1 are associated with disorders exhibiting increased connective tissue turnover,such as rheumatoid,arthritis,osteoarthritis,scleroderma,and cirrhosis of liver,but is produced in cartilage from old donors or patients with osteoarthritis.CHI3L1 is abnormally expressed in the hippocampus of subjects with schizophrenia and may be involved in the cellular response to various environmental events that are reported to increase the risk of schizophrenia. |
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