CXCL12/SDF1 Polyclonal Antibody
Price:
Size:
200μL
100μL
50μL
20μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB
| Verified Samples |
Verified Samples in WB:THP-1,Raw264.7,Rat testis |
| Dilution | WB 1:2000-4000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant Rat CXCL12 protein expressed by E.coli. |
| Abbre | CXCL12 |
| Synonyms | Cxcl12; SDF-1抗体 |
| Swissprot | |
| Calculated MW | 10kDa |
| Observed MW | 10kDa |
| Cellular Localization | Secreted |
| Concentration | 1mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol,pH 7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Immunology;Microbiology;Cardiovascular |
| Conjugation | Unconjugated |
| Background | The stromal cell derived factor 1 (SDF1/CXCL12) is a small, pro-inflammatory chemoattractant cytokine that regulates leukocyte trafficking through interactions with its cognate 7-transmembrane G protein-coupled receptors. The SDF1/CXCL12 receptor, CXCR4, also serves as a coreceptor for the entry of human immunodeficiency virus into target cells. SDF1/CXCL12 may regulate homing and maintenance of CXCR4-expressing stem or progenitor cells, including embryonic and many somatic stem cells. Many cancer cells express CXCR4, suggesting that SDF1/CXCL12 plays a role in cancer metastasis. Alternative splicing and differential processing during maturation produce a pair of SDF1/CXCL12 isoforms (SDF1/CXCL12α and SDF1/CXCL12β) that have different properties and biological activities. Additional isoforms of SDF1/CXCL12 have been reported. |
Western blotting with anti-CXCL12 polyclonal antibody at dilution of 1:2000. Lane 1: THP-1 cell lysate, lane 2: Raw264.7 cell lysate, lane 3: K562 cell lysate for negative control.
Western blot of Rat testis with CXCL4 polyclonal antibody at 1:1000 dilution.
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| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
