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DEFA1 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: WB
Verified Samples
Verified Samples in WB:Human lung
Dilution
WB 1:500-1:1000
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human DEFA1
Abbre
DEFA1
Synonyms
DEF1;DEF3;DEFA1;DEFA2;DEFA3;Defensin alpha 1;Defensin alpha 2;Defensin alpha 3;HNP1;HNP3;HP1;HP3;MRS;Neutrophil defensin 1;Neutrophil defensin 2;Neutrophil defensin 3
Swissprot
Calculated MW
10kDa
Cellular Localization
Secreted
Concentration
0.4 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Immunology; Microbiology
Conjugation
Unconjugated
Background
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.
Western Blot analysis of Human lung tissue using DEFA1 Polyclonal Antibody at dilution of 1:550
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