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E-Cadherin Monoclonal Antibody

Price: ¥2310 ¥1420

Size:
120μL 60μL
  • 宿主: Mouse
  • 反应性: Mouse;Rat
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Mouse liver,Rat colon,Rat pancreas
Dilution
IHC 1:200-1:800
Clonality
Monoclonal
Isotype
IgG
Immunogen
Recombinant protein corresponding to MouseE-cadherin
Abbre
E-Cadherin
Synonyms
Arc 1;CADH1;Cadherin 1;cadherin 1 type 1 E-cadherin;Cadherin1;CAM 120/80;CD 324;CD324;CD324 antigen;cdh1;CDHE;E-Cad/CTF3;E-cadherin;ECAD;Epithelial cadherin;epithelial calcium dependant adhesion protein;LCAM;Liver cell adhesion molecule;UVO;Uvomorulin抗体
Swissprot
Concentration
1.6 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Developmental Biology; Signal Transduction
Clone No.
EC125D
Conjugation
Unconjugated
Background
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.
Immunohistochemistry analysis of paraffin-embedded mouse liver using E-Cadherin Monoclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat colon using E-Cadherin Monoclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat pancreas using E-Cadherin Monoclonal Antibody at dilution of 1:300.


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