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FAS Monoclonal Antibody

Price: ¥2310 ¥1420

Size:
120μL 60μL
  • 宿主: Mouse
  • 反应性: Human;Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human gallbladder,Mouse colon,Mouse testis
Dilution
IHC 1:200-1:800
Clonality
Monoclonal
Isotype
IgG
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse FAS
Abbre
FAS
Synonyms
ALPS 1A;ALPS1A;APO 1;Apo 1 antigen;APO 1 cell surface antigen;Apo-1 antigen;APO1;Apo1 antigen;APO1 cell surface antigen;Apoptosis antigen 1;Apoptosis mediating surface antigen FAS;Apoptosis-mediating surface antigen FAS;APT 1;APT1;CD 95;CD 95 antigen;CD95;CD95 antigen;Delta Fas;Delta Fas/APO 1/CD95;Delta Fas/APO1/CD95;Fas (TNF receptor superfamily;member 6);FAS 1;FAS 827dupA;Fas AMA;Fas;FAS Antigen;Fas cell surface death receptor;FAS1;FASLG receptor;FASTM;sFAS;Surface antigen APO1;TNF receptor superfamily;member 6;TNFRSF 6;TNFRSF6;TNR6;Tumor necrosis factor receptor superfamily member 6抗体
Swissprot
Concentration
420 μg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Cell Biology; Immunology
Clone No.
10E5B10
Conjugation
Unconjugated
Background
FAS,also named as CD95,APO-1,APT1,FAS1 and TNFRSF6,is a receptor for TNFSF6/FASLG. It is a cell surface receptor belonging to the TNF receptor superfamily,can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains,leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance,in the antigen-stimulated suicide of mature T-cells,or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). This anti-Fas monoclonal antibody can be used to induce apoptosis in cell cultures through Fas by imitating the Fas-ligand.
Immunohistochemistry analysis of paraffin-embedded human gallbladder using FAS Monoclonal Antibody at dilution of 1:200.
Immunohistochemistry analysis of paraffin-embedded mouse colon using FAS Monoclonal Antibody at dilution of 1:200.
Immunohistochemistry analysis of paraffin-embedded mouse testis using FAS Monoclonal Antibody at dilution of 1:200.


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