FAS Monoclonal Antibody
Price:
Size:
120μL
60μL
- 宿主: Mouse
- 反应性: Human;Mouse
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human gallbladder,Mouse colon,Mouse testis |
Dilution | IHC 1:200-1:800 |
Clonality | Monoclonal |
Isotype | IgG |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse FAS |
Abbre | FAS |
Synonyms | ALPS 1A;ALPS1A;APO 1;Apo 1 antigen;APO 1 cell surface antigen;Apo-1 antigen;APO1;Apo1 antigen;APO1 cell surface antigen;Apoptosis antigen 1;Apoptosis mediating surface antigen FAS;Apoptosis-mediating surface antigen FAS;APT 1;APT1;CD 95;CD 95 antigen;CD95;CD95 antigen;Delta Fas;Delta Fas/APO 1/CD95;Delta Fas/APO1/CD95;Fas (TNF receptor superfamily;member 6);FAS 1;FAS 827dupA;Fas AMA;Fas;FAS Antigen;Fas cell surface death receptor;FAS1;FASLG receptor;FASTM;sFAS;Surface antigen APO1;TNF receptor superfamily;member 6;TNFRSF 6;TNFRSF6;TNR6;Tumor necrosis factor receptor superfamily member 6抗体 |
Swissprot | |
Concentration | 420 μg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Cell Biology; Immunology |
Clone No. | 10E5B10 |
Conjugation | Unconjugated |
Background | FAS,also named as CD95,APO-1,APT1,FAS1 and TNFRSF6,is a receptor for TNFSF6/FASLG. It is a cell surface receptor belonging to the TNF receptor superfamily,can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains,leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance,in the antigen-stimulated suicide of mature T-cells,or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). This anti-Fas monoclonal antibody can be used to induce apoptosis in cell cultures through Fas by imitating the Fas-ligand. |
Immunohistochemistry analysis of paraffin-embedded human gallbladder using FAS Monoclonal Antibody at dilution of 1:200.
Immunohistochemistry analysis of paraffin-embedded mouse colon using FAS Monoclonal Antibody at dilution of 1:200.
Immunohistochemistry analysis of paraffin-embedded mouse testis using FAS Monoclonal Antibody at dilution of 1:200.
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