GCG Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
- 宿主: Rabbit
- 反应性: Mouse;Rat
- 应用性: WB
Verified Samples |
Verified Samples in WB:Mouse pancreas,Mouse pancreas,Rat pancreas,Rat pancreas |
Dilution | WB 1:500-1:2000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Glucagon |
Abbre | GCG |
Synonyms | GCG;GLP 2;GLP1;GLP2;glucagon;GRPP;Glucagon like peptide 1;GRPP Oxyntomodulin;OXM;Proglucagon |
Swissprot | |
Calculated MW | 21kDa |
Observed MW | 25kDa |
Cellular Localization | Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP-1 and GLP-2 are also secreted in selected neurons in the brain. |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Metabolism; Developmental Biology; Signal Transduction; Stem Cells |
Conjugation | Unconjugated |
Background | The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. |
Western Blot analysis of various samples using GCG Polyclonal Antibody at dilution of 1:1000.
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IF: 6.656Journal:PHYTOMEDICINE
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