GDF-8 Polyclonal Antibody
Price:
Size:
100μL
50μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB
| Verified Samples |
Verified Samples in WB:Hela,Mouse heart,Rat heart,Rat skeletal muscle |
| Dilution | WB 1:500-1:1000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant Human GDF-8 Protein expressed by E.coli |
| Abbre | GDF-8 |
| Synonyms | Growth/differentiation factor 8;GDF-8;Myostatin;MSTN;GDF8 |
| Swissprot | |
| Calculated MW | 43kDa |
| Observed MW | 35kDa-43kDa |
| Concentration | 1mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide,50% glycerol pH 7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer;Signal Transduction |
| Conjugation | Unconjugated |
| Background | Growth/differentiation factor 8(Mstn,GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer,and interacts with WFIKKN2,leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues. |
Western blot with GDF-8 Polyclonal antibody at dilution of 1:1000.lane 1:Hela whole cell lysate,lane 2:Mouse heart,lane 3:Rat heart,lane 4:Rat skeletal muscle
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
