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GDF-8 Polyclonal Antibody

GDF-8 Polyclonal Antibody
  • GDF-8 Polyclonal Antibody
  • GDF-8 Polyclonal Antibody

Price: ¥2100.00 ¥800.00

Size:
100 μL 25 μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: WB
Verified Samples
Verified Samples in WB: Hela, Mouse heart, Rat heart, Rat skeletal muscle
Dilution
WB 1:500-1:1000
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant Human GDF-8 Protein expressed by E.coli
Abbre
GDF-8
Synonyms
GDF-8, GDF8, Growth/differentiation factor 8, MSTN, Myostatin
Swissprot
Calculated MW
43 kDa
Observed MW
35 kDa-43 kDa
Concentration
1 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4
Purification Method
Antigen Affinity Purification
Research Areas
Cancer, Signal Transduction
Conjugation
Unconjugated
Background
Growth/differentiation factor 8(Mstn,GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer,and interacts with WFIKKN2,leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues.
Western blot with GDF-8 Polyclonal antibody at dilution of 1:1000.lane 1:Hela whole cell lysate,lane 2:Mouse heart,lane 3:Rat heart,lane 4:Rat skeletal muscle
E-AB-1003 Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) 500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1043 Streptavidin(peroxidase/HRP conjugated) 500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1194 HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed 500 μL , 120 μL , 1 mL
E-IR-R304A Western Blot Detection Kit 50 Assays
E-IR-R304B High Accuracy and Absorbability Western Blot Detection Kit 50 Assays


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