GREM1 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB
| Verified Samples |
Verified Samples in WB:Mouse testis |
| Dilution | WB 1:500-1:2000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein of human GREM1 |
| Abbre | GREM1 |
| Synonyms | BMP antagonist 1;Cell proliferation inducing gene 2 protein;Cell proliferation-inducing gene 2 protein;CKTSF1B1;colorectal adenoma and carcinoma 1;Cysteine knot superfamily 1;Cysteine knot superfamily 1;BMP antagonist 1;Cysteine knot superfamily BMP antagonist 1;DAN domain family member 2;DAND2;Down regulated in Mos-transformed cells protein;Down-regulated in Mos-transformed cells protein;DRM;grem1;GREM1;Gremlin 1 homolog;cysteine knot superfamily;Gremlin 1 like protein;Gremlin 1;cysteine knot superfamily;homolog;GREMLIN;Gremlin-1;Gremlin1;IHG-2;IHG2;Increased in high glucose 2;Increased in high glucose protein 2;PIG2;Proliferation inducing gene 2;proliferation inducing gene 2 protein抗体 |
| Swissprot | |
| Calculated MW | 21kDa |
| Cellular Localization | Secreted. |
| Concentration | 0.3 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Signal Transduction; Stem Cells |
| Conjugation | Unconjugated |
| Background | This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Western Blot analysis of Mouse testis tissue using GREM1 Polyclonal Antibody at dilution of 1:700
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
