GSK3 beta Polyclonal Antibody

Verified Samples in WB:Hela,HepG2,C6,Mouse lung
Verified Samples in IHC:Human ovary cancer,Mouse brain,Rat testis
Verified Samples in IF:Human liver cancer

WB 1:500-1:2000, IHC 1:300-1:800, IF 1:200-1:500

Polyclonal

IgG

KLH conjugated Synthetic peptide corresponding to Mouse GSK3β

GSK3 beta

Glycogen Synthase Kinase 3 Beta;Glycogen synthase kinase-3 beta;GSK 3 beta;GSK-3 beta;GSK3B;GSK3B;GSK3beta isoform;Serine/threonine-protein kinase GSK3B抗体

47kDa

47kDa

Cytoplasm. Nucleus. Cell membrane. The phosphorylated form shows localization to cytoplasm and cell membrane. The MEMO1-RHOA-DIAPH1 signaling pathway controls localization of the phosophorylated form to the cell membrane.

2 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Affinity purification

Cancer; Cardiovascular; Metabolism; Neuroscience; Signal Transduction; Stem Cells

Unconjugated

The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease.