KI67 Monoclonal Antibody
Price:
Size:
120μL
60μL
20μL
- 宿主: Mouse
- 反应性: Human;Mouse;Rat
- 应用性: IHC-p;IF
Verified Samples |
Verified Samples in IHC:Human plasmacytoma Verified Samples in IF:Rat brain |
Dilution | IHC 1:100-1:300, IF 1:50-200 |
Clonality | Monoclonal |
Isotype | IgG |
Immunogen | Synthetic Peptide |
Abbre | Ki 67 |
Synonyms | Antigen identified by monoclonal Ki 67;Antigen identified by monoclonal Ki-67;Antigen KI-67;Antigen KI67;Antigen Ki67;KI67;KIA;Marker of proliferation Ki-67;MIB 1;MIB;MKI67;PPP1R105;Proliferation marker protein Ki-67;Proliferation related Ki 67 antigen;Protein phosphatase 1 regulatory subunit 105;RP11-380J17.2抗体 |
Swissprot | |
Cellular Localization | Nucleus |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method | Protein A purification |
Research Areas | Cancer; Cell Biology; Neuroscience; Tags and Cell Markers |
Clone No. | Clone:8K5 |
Conjugation | Unconjugated |
Background | Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551). Does not contribute to the internal structure of mitotic chromosomes (By similarity). May play a role in chromatin organization (PubMed:24867636). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable). |
Immunohistochemistry of paraffin-embedded Human Plasmacytoma using KI67 Monoclonal Antibody at dilution of 1:200.
Immunofluorescence analysis of Rat brain tissue using KI67 Monoclonal Antibody at dilution of 1:200.
-
Exposure to intrauterine diabetes and post-natal high-fat diet: Effects on the endocrine pancreas of adult rat female pups
IF: 6.78 -
Regorafenib enhances antitumor immune efficacy of anti-PD-L1 immunotherapy on oral squamous cell carcinoma
IF: 6.53
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |