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LTF Polyclonal Antibody

Price: ¥1640 ¥1010

Size:
100μL 50μL
  • 宿主: Rabbit
  • 反应性: Mouse
  • 应用性: WB
Verified Samples
Verified Samples in WB:Mouse spleen
Dilution
WB 1:500-1:1000
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant Mouse LTF protein expressed by Mammalian
Abbre
LTF
Synonyms
Lactotransferrin;EC:3.4.21.;Lactoferrin;Ltf
Swissprot
Calculated MW
78kDa
Observed MW
80kDa
Concentration
1mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.02% sodium azide,50% glycerol pH 7.4
Purification Method
Antigen Affinity Purification
Conjugation
Unconjugated
Background
Lactotransferrin is a major iron-binding and multifunctional protein found in exocrine fluids such as breast milk and mucosal secretions. Has antimicrobial activity. Antimicrobial properties may include bacteriostasis,which is related to its ability to sequester free iron and thus inhibit microbial growth,as well as direct bactericidal properties leading to the release of lipopolysaccharides from the bacterial outer membrane. May have anabolic,differentiating and anti-apoptotic effects on osteoblasts and may also inhibit osteoclastogenesis,possibly playing a role in the regulation of bone growth. May interfere with the lipopolysaccharide (LPS)-stimulated TLR4 signaling.The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Shows a preferential cleavage at -Arg-Ser-Arg-Arg-|- and -Arg-Arg-Ser-Arg-|-,and of Z-Phe-Arg-|-aminomethylcoumarin sites.
Western blot with LTF Polyclonal antibody at dilution of 1:1000.lane 1: Mouse spleen
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