MAP1LC3B Monoclonal Antibody
Price:
Size:
120μL
60μL
20μL
- 宿主： Mouse
- 反应性： Human
- 应用性： IHC-p
| Verified Samples |
Verified Samples in IHC:Human brain |
| Dilution | IHC 1:100-200 |
| Clonality | Monoclonal |
| Isotype | IgG |
| Immunogen | Recombinant Protein of LC3B of MAP1LC3B |
| Abbre | MAP1LC3B |
| Synonyms | ATG8F;Autophagy-related protein LC3 B;Autophagy-related ubiquitin-like modifier LC3 B;LC3B;LC3II;MAP1 light chain 3 like protein 2;MAP1 light chain 3-like protein 2;MAP1A/1BLC3;MAP1A/MAP1B LC3 B;MAP1A/MAP1B light chain 3 B;MAP1ALC3;MAP1LC3B a;Map1lc3b;Microtubule associated protein 1 light chain 3 beta;Microtubule-associated protein 1 light chain 3 beta;Microtubule-associated proteins 1A/1B light chain 3B;MLP3B抗体 |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytoskeleton. Endomembrane system. Cytoplasmic vesicle>autophagosome membrane. LC3-II binds to the autophagic membranes. |
| Tissue Specificity | Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver. |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4 |
| Purification Method | Protein A purification |
| Research Areas | Cancer; Cardiovascular; Metabolism; Neuroscience; Signal Transduction |
| Clone No. | Clone:6E4 |
| Conjugation | Unconjugated |
| Background | The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.
MAP1LC3B (Microtubule Associated Protein 1 Light Chain 3 Beta) is a Protein Coding gene. Diseases associated with MAP1LC3B include Sporadic Pheochromocytoma and Lacrimal Gland Adenocarcinoma. Among its related pathways are Vesicle-mediated transport and Senescence and Autophagy in Cancer. GO annotations related to this gene include microtubule binding. An important paralog of this gene is MAP1LC3B2. |
Immunohistochemistry of paraffin-embedded Human brain tissue using MAP1LC3B Monoclonal Antibody at dilution of 1:200.
| E-AB-1001 | Goat Anti-Mouse IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1024 | Goat Anti-Mouse IgG(H+L)(Biotin conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1196 | HRP-Goat Anti-Mouse IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
