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MBL2/MBP-C Polyclonal Antibody

MBL2/MBP-C Polyclonal Antibody
  • MBL2/MBP-C Polyclonal Antibody
  • MBL2/MBP-C Polyclonal Antibody
  • MBL2/MBP-C Polyclonal Antibody

Price: ¥2100.00 ¥800.00

Size:
100 μL 25 μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: WB
Verified Samples
Verified Samples in WB: Human plasma, Human HepG2, Mouse liver, Mouse kidney, Rat kidney
Dilution
WB 1:500-1:1000
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant Human MBL2/MBP-C protein expressed by E.coli
Abbre
MBL2/MBP-C
Synonyms
2, COLEC 1, COLEC1, Collectin-1, HSMBPC, Lectin, Mannan binding lectin, Mannan binding protein, Mannan-binding protein, Mannose bindi, Mannose binding lectin (protein C) 2, Mannose binding lectin (protein C) 2 soluble, mannose-binding, soluble, soluble (opsonic defect)
Swissprot
Calculated MW
26 kDa
Observed MW
26 kDa
Cellular Localization
Secreted
Tissue Specificity
Plasma protein produced mainly in the liver.
Concentration
1 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4
Purification Method
Antigen Affinity Purification
Research Areas
Cancer, Immunology
Conjugation
Unconjugated
Background
Mannose-binding Lectin (MBL) is an acute phase protein bearing to the family of collectins produced by the liver as a monomer that forms a triple helix. Once released in serum,it further polymerizes forming dimers to octamers. The degree of serum polymerization is critical for the biological activity of MBL. MBL has higher affinity to microbial polysaccharides or their glycoconjugates. MBL was shown earlier to bind cell surfaces of bacteria,fungi,protozoa and viruses and acts as an acute-phase plasma protein (APP) during infection and inflammation. MBL activates the lectin-complement pathway,promotes opsonophagocytosis and modulates inflammation.
Western blot with MBL2/MBP-C Polyclonal antibody at dilution of 1:1000.lane 1:Human plasma,lane 2:HepG2 whole cell lysate
Western blot with MBL2/MBP-C Polyclonal antibody at dilution of 1:1000.lane 1:Mouse liver,lane 2:Mouse kidney,lane 3:Rat kidney
E-AB-1003 Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) 500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1043 Streptavidin(peroxidase/HRP conjugated) 500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1194 HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed 500 μL , 120 μL , 1 mL
E-IR-R304A Western Blot Detection Kit 50 Assays
E-IR-R304B High Accuracy and Absorbability Western Blot Detection Kit 50 Assays


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