Phospho-CREB1 (Ser133) Polyclonal Antibody
Price:
Size:
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: WB;IHC-p;IF
Verified Samples |
Verified Samples in WB:MCF-7,A549,K562,HEK293 Verified Samples in IHC:Human uterus Verified Samples in IF:Mouse lung |
Dilution | WB 1:500-1:2000, IHC 1:100-1:300, IF 1:100-1:300 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthesized peptide derived from human CREB-1 around the phosphorylation site of Ser133 |
Abbre | CREB-1 (phospho Ser133) |
Synonyms | Active transcription factor CREB;cAMP response element binding protein 1;cAMP response element binding protein;cAMP responsive element binding protein 1;cAMP-responsive element-binding protein 1;CREB;CREB-1;CREB1;CREB1;Cyclic AMP-responsive element-binding protein 1;MGC9284;OTTHUMP00000163864;OTTHUMP00000163865;OTTHUMP00000206660;OTTHUMP00000206662;OTTHUMP00000206667;Transactivator protein抗体 |
Swissprot | |
Calculated MW | 37kDa |
Observed MW | 37kDa |
Cellular Localization | Nucleus. |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Epigenetics and Nuclear Signaling; Immunology |
Conjugation | Unconjugated |
Background | This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity. |
Western Blot analysis of various cells using Phospho-CREB1 (Ser133) Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human uterus tissue using Phospho-CREB1 (Ser133) Polyclonal Antibody at dilution of 1:200
Immunofluorescence analysis of Mouse lung tissue using Phospho-CREB1 (Ser133) Polyclonal Antibody at dilution of 1:200
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Oleuropein confers neuroprotection against rotenone-induced model of Parkinson’s disease via BDNF/CREB/Akt pathway
IF: 4.996Journal:Scientific Reports
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E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |