Phospho-SMAD2/3 (Thr8) Polyclonal Antibody
Price:
Size:
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: WB
Verified Samples |
Verified Samples in WB:VEC |
Dilution | WB 1:500-1:2000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthesized peptide derived from human Smad2/3 around the phosphorylation site of Thr8 |
Abbre | Smad2/3 (phospho Thr8) |
Synonyms | SMAD2;MADH2;MADR2;Mothers against decapentaplegic homolog 2;MAD homolog 2;Mothers against DPP homolog 2;JV18-1;Mad-related protein 2;hMAD-2;SMAD family member 2;SMAD 2;Smad2;hSMAD2;SMAD3;MADH3;Mothers against decapentaplegic抗体 |
Swissprot | |
Calculated MW | 48kDa |
Observed MW | 48kDa |
Cellular Localization | Cytosol,Nucleus,heteromeric SMAD protein complex,nuclear chromatin,nuclear inner membrane,nucleoplasm,nucleus,Plasma Membrane,Other locations:cytoplasm,receptor complex,SMAD protein complex,transcription factor complex |
Tissue Specificity | SMAD2 is Expressed at high levels in skeletal muscle, endothelial cells, heart and placenta. |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Epigenetics and Nuclear Signaling; Signal Transduction; Stem Cells |
Conjugation | Unconjugated |
Background | SMAD is a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. They mediate the signal of the transforming growth factor (TGF)-beta, and thus regulate multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. |
Western Blot analysis of VEC cells with Phospho-Smad2/3 (Thr8) Polyclonal Antibody
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Neutrophils direct preexisting matrix to initiate repair in damaged tissues
IF: 25.606 -
Flavonoids and Omega3 Prevent Muscle and Cardiac Damage in Duchenne Muscular Dystrophy Animal Model
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MiR-130a-3p Alleviates Inflammatory and Fibrotic Phases of Pulmonary Fibrosis Through Proinflammatory Factor TNF-α and Profibrogenic Receptor TGF-βRII
IF: 5.811Journal:Frontiers in Pharmacology -
Farrerol Ameliorated Cisplatin-Induced Chronic Kidney Disease Through Mitophagy Induction via Nrf2/PINK1 Pathway
IF: 5.811Journal:Frontiers in Pharmacology -
miRNAs through β-ARR2/p-ERK1/2 pathway regulate the VSMC proliferation and migration
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Hydroxysafflor yellow A mitigates myocardial fibrosis induced by isoproterenol and angiotensin II
IF: 3.94Journal:American Journal of Translational ResearchPMID:36628216 -
PTX3 Predicts Myocardial Damage and Fibrosis in Duchenne Muscular Dystrophy
IF: 3.367
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E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |