ROCK2 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human; Mouse; Rat
- 应用性： WB
| Verified Samples |
Verified Samples in WB:Mouse brain,Rat brain,HepG2 |
| Dilution | WB 1:500-1:2000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Fusion protein of human ROCK2 |
| Abbre | ROCK2 |
| Synonyms | coiled-coil-containing protein kinase 2;KIAA0619;p164 ROCK 2;p164 ROCK-2;Rho associated coiled coil containing protein kinase 2;Rho associated protein kinase 2;Rho associated;coiled coil containing protein kinase II;Rho kinase 2;Rho-associated;Rho-associated protein kinase 2;ROCK 2;Rock II;Rock2;ROCK2;Rock2m;ROK alpha;ROKalpha |
| Swissprot | |
| Calculated MW | 161 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytoplasm. Cell membrane. Cytoplasmic, and associated with actin microfilaments and the plasma membrane. |
| Concentration | 0.78 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer; Cell Biology; Signal Transduction |
| Conjugation | Unconjugated |
| Background | The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. |
Western blot analysis of Mouse brain tissue Rat brain tissue and HepG2 cell lysates using ROCK2 Polyclonal Antibody at dilution of 1:400
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
