SEPP1 Polyclonal Antibody

Verified Samples in WB:Human serum
Verified Samples in IF:HepG2,C6

WB 1:500-1:1000,IF 1:50-1:200

Polyclonal

IgG

Recombinant Human SEPP1 protein expressed by E.coli

SEPP1

Selenoprotein P;SeP;SELENOP;SELP;SEPP1

43kDa

50kDa

1mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide,50% glycerol pH 7.4

Antigen Affinity Purification

Unconjugated

Selenoprotein P (SeP) is an extracellular,monomeric glycoprotein containing up to 10 selenocysteine residues in the polypeptide chain. It is ubiquitously expressed in mammalian tissues,and in human plasma it accounts for at least 40% of the total selenium concentration. SeP binds to heparin and cell membranes,and is associated with endothelial cells. SeP in human plasma protects against peroxynitrite-mediated oxidation and reduces phospholipid hydroperoxide in vitro,in accordance with the presumption that it has a function as an extracellular oxidant defense. Immunochemical assays have demonstrated that its concentration in plasma varies much with selenium intake,but other factors also have an influence.