Serpina1 Polyclonal Antibody
Price:
Size:
100μL
50μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB
| Verified Samples |
Verified Samples in WB:Human Hep G2,Mouse Kidney,Mouse Liver,Rat Kidney,Rat Liver |
| Dilution | WB 1:500-1000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant Rat Serpina1 protein expressed by E.coli |
| Abbre | Serpina1 |
| Synonyms | A1A;A1AT;A1AT;AAT;Alpha 1 antiproteinase;Alpha 1 antitrypsin;Alpha 1 antitrypsin null;Alpha 1 protease inhibitor;Alpha-1 protease inhibitor;Alpha-1-antiproteinase;alpha1 proteinase inhibitor;Alpha1AT;Dom1;PI;PI1;PRO2275;Serine (or cysteine) proteinase inhibitor clade A member 1;Serine protease inhibitor 1-1;Serine protease inhibitor A1a;Serpin A1;Serpin A1a;Serpin peptidase inhibitor clade A member 1;Serpina1;Short peptide from AAT;SPAAT;Spi1-1 |
| Swissprot | |
| Calculated MW | 46kDa |
| Observed MW | 43kDa,50kDa |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH 7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Cardiovascular; Metabolism |
| Conjugation | Unconjugated |
| Background | SERPINA1 is the gene for a protein called alpha-1-antitrypsin (AAT),which is a serine protease inhibitor whose targets include elastase,plasmin,thrombin,trypsin,chymotrypsin,and plasminogen activator. AAT is a glycoprotein synthesized primarily by hepatocytes,with smaller amountssynthesized by intestinal epithelial cells,neutrophils,pulmonary alveolar cells and macrophages. AAT is the most abundant,endogenous serine protease inhibitor in blood circulation and it has been implicated in regulating vital fluid phase biological events such as blood coagulation,fibrinolysis,complement activation,apoptosis,reproduction,tumor progression and inflammatory response. The primary function of AAT is thought to be the inactivation of neutrophil elastase and other endogenous serine proteases. Defects in SERPINA1 can cause emphysema or liver disease. |
Western blot with Serpina1 Polyclonal antibody at dilution of 1:500.lane 1:Hep G2 whole cell lysate,lane 2：Mouse kidney,lane 3：Mouse liver,lane 4：Rat kidney,lane 5：Rat liver
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
