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SIRT3 Polyclonal Antibody

Price: ¥3300 ¥2220 ¥1380

Size:
200μL 120μL 60μL
  • 宿主: Rabbit
  • 反应性: Mouse
  • 应用性: WB
Verified Samples
Verified Samples in WB:Mouse heart,Mouse skeletal muscle,Mouse kidney
Dilution
WB 1:500-1:2000
Clonality
Polyclonal
Isotype
IgG
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse SIRT3
Abbre
SIRT3
Synonyms
hSIRT 3;hSIRT3;Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase;NAD dependent deacetylase sirtuin 3 mitochondrial;NAD-dependent protein deacetylase sirtuin-3;mitochondrial;Regulatory protein SIR2 homolog 3;Silent mating type information regulation 2 S.cerevisiae homolog 3;Sir 2 like 3;SIR 2 like protein 3;SIR 3;SIR2 L3;Sir2 like 3;SIR2 like protein 3;SIR2-like protein 3;SIR2L3;SIR3;SIRT 3;SIRT3;Sirtuin 3;Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae);Sirtuin type 3;Sirtuin3
Swissprot
Calculated MW
28kDa
Observed MW
28kDa
Cellular Localization
Mitochondrion matrix.
Concentration
500 μg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Cell Biology; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism
Conjugation
Unconjugated
Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.
Western Blot analysis of various samples using SIRT3 Polyclonal Antibody at dilution of 1:600.
E-AB-1003 Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) 500μL , 120μL , 60μL , 30μL , 1mL
E-AB-1043 Streptavidin(peroxidase/HRP conjugated) 500μL , 120μL , 60μL , 30μL , 1mL
E-AB-1194 HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed 500μL , 120μL , 1mL
E-IR-R304A Western Blot Detection Kit 50Assays
E-IR-R304B High Accuracy and Absorbability Western Blot Detection Kit 50Assays


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