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SNCA Polyclonal Antibody

SNCA Polyclonal Antibody
  • SNCA Polyclonal Antibody
  • SNCA Polyclonal Antibody

Price: ¥2100.00 ¥800.00

Size:
100 μL 25 μL
  • 宿主: Rabbit
  • 反应性: Human;mouse;Rat
  • 应用性: WB
Verified Samples
Verified Samples in WB: SH-SY5Y, Mouse brain, Rat brain
Dilution
WB 1:500-1:1000
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant Human SNCA protein expressed by E.coli
Abbre
SNCA
Synonyms
PARK1, NACP, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, SNCA
Swissprot
Calculated MW
14 kDa
Observed MW
16 kDa
Concentration
1 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4
Purification Method
Antigen Affinity Purification
Research Areas
Cancer, Neuroscience
Conjugation
Unconjugated
Background
Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release.Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores.Mechanistically, acts by increasing local Ca2+ release from microdomains which is essential for the enhancement of ATP-induced exocytosis.Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5.
Western blot with SNCA Polyclonal antibody at dilution of 1:500.lane 1:SH-SY5Y whole cell lysate, lane 2:Mouse brain, lane 3:Rat brain
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