Survivin Monoclonal Antibody
Price:
Size:
120μL
60μL
20μL
- 宿主： Mouse
- 反应性： Human;Rat
- 应用性： WB;IHC-p
| Verified Samples |
Verified Samples in WB:Hela,293T,PC12 Verified Samples in IHC:Mouse brain |
| Dilution | WB 1:1000-2000;IHC 1:50-1:200 |
| Clonality | Monoclonal |
| Isotype | IgG |
| Immunogen | Recombinant Protein |
| Abbre | Survivin |
| Synonyms | API4;Apoptosis inhibitor 4;Apoptosis inhibitor survivin;Apoptosis inhibitor4;Baculoviral IAP repeat containing 5;Baculoviral IAP repeat containing protein 5;Baculoviral IAP repeat-containing protein 5;BIRC 5;BIRC5;BIRC5;EPR 1;IAP4;Survivin variant 3 alpha;SVV;TIAP抗体 |
| Swissprot | |
| Observed MW | 16kDa |
| Cellular Localization | Cytoplasm. Nucleus. Chromosome. Chromosome>centromere. Cytoplasm>cytoskeleton>spindle. Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis. Colocalizes with AURKB at mitotic chromosomes. |
| Tissue Specificity | Expressed only in fetal kidney and liver, and to lesser extent, lung and brain. Abundantly expressed in adenocarcinoma (lung, pancreas, colon, breast, and prostate) and in high-grade lymphomas. Also expressed in various renal cell carcinoma cell lines. |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
| Purification Method | Protein A purification |
| Research Areas | Cancer; Cell Biology; Neuroscience |
| Clone No. | Clone:4E2 |
| Conjugation | Unconjugated |
| Background | This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Western Blot analysis of 1) Hela, 2) 293T, 3) PC-12 cells with Survivin Monoclonal Antibody
Immunohistochemistry of paraffin-embedded Mouse brain tissue using Survivin Monoclonal Antibody at dilution of 1:200.
| E-AB-1001 | Goat Anti-Mouse IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1024 | Goat Anti-Mouse IgG(H+L)(Biotin conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1196 | HRP-Goat Anti-Mouse IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
