• 本公司产品仅供体外研究使用,不用于临床诊断

Tau Polyclonal Antibody

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    产品货号:E-AB-70075

    别称:AI413597,AW045860,DDPAC,FLJ31424,FTDP 17,G protein beta1/gamma2 subunit interacting factor 1,MAPT,MAPTL,MGC134287,MGC138549,MGC156663,Microtubule associated protein tau,Microtubule associated protein tau isoform 4,Microtubule-associated protein tau,MSTD,Mtapt,MTBT1,MTBT2,Neurofibrillary tangle protein,Paired helical filament tau,Paired helical filament-tau,PHF tau,PHF-tau,PPND,PPP1R103,Protein phosphatase 1,regulatory subunit 103,pTau,RNPTAU,TAU,TAU,Tauopathy and respiratory failure,included

    规格:
    • 60μL
    • 120μL
    • 200μL
    数量:
    - +
    价格: ¥960

    宿主: Rabbit

    反应性: H,M,R

    应用: WB,IHC

    Overview

    Synonyms AI413597,AW045860,DDPAC,FLJ31424,FTDP 17,G protein beta1/gamma2 subunit interacting factor 1,MAPT,MAPTL,MGC134287,MGC138549,MGC156663,Microtubule associated protein tau,Microtubule associated protein tau isoform 4,Microtubule-associated protein tau,MSTD,Mtapt,MTBT1,MTBT2,Neurofibrillary tangle protein,Paired helical filament tau,Paired helical filament-tau,PHF tau,PHF-tau,PPND,PPP1R103,Protein phosphatase 1,regulatory subunit 103,pTau,RNPTAU,TAU,TAU,Tauopathy and respiratory failure,included
    Swissprot P10636,P10637,P19332
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen KLH conjugated Synthetic peptide corresponding to Mouse Tau
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R217)
    Recommended dilution WB 1:500-1:2000, IHC 1:100-1:500
    Concentration 150 μg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm>cytosol. Cell membrane. Cytoplasm>cytoskeleton. Cell projection>axon. Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components.
    Tissue specificity Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.Highest expression level in parietal lobe.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
    Background This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

    Images

    • Western Blot analysis of various samples using Tau Polyclonal Antibody at dilution of 1:1000.

    • Immunohistochemistry analysis of paraffin-embedded human brain using Tau Polyclonal Antibody at dilution of 1:100.

    • Immunohistochemistry analysis of paraffin-embedded rat brain using Tau Polyclonal Antibody at dilution of 1:100.

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