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UNC45B Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse
  • 应用性: WB
Verified Samples
Verified Samples in WB:Mouse skeletal muscle
Dilution
WB 1:500-1:2000
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human UNC45B
Abbre
UNC45B
Synonyms
Cardiomyopathy associated 4 ;CMYA4 ;FLJ38610;MGC119540;MGC119541;OTTHUMP00000163855;Protein unc 45 homolog B;Protein unc-45 homolog B;SMUNC45;Striated muscle UNC45;UN45B;Unc 45 homolog B (C. elegans);Unc 45 homolog B;UNC 45B;UNC-45B;UNC45 ;UNC45B抗体
Swissprot
Calculated MW
104/95 kDa
Observed MW
Refer to figures
Cellular Localization
Cytoplasm>cytosol.
Concentration
0.8 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Developmental biology; Signal transduction
Conjugation
Unconjugated
Background
This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants.
Western blot analysis of Mouse skeletal muscle tissue lysate using UNC45B Polyclonal Antibody at dilution of 1:600
E-AB-1003 Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) 500μL , 120μL , 60μL , 30μL , 1mL
E-AB-1043 Streptavidin(peroxidase/HRP conjugated) 500μL , 120μL , 60μL , 30μL , 1mL
E-AB-1194 HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed 500μL , 120μL , 1mL
E-IR-R304A Western Blot Detection Kit 50Assays
E-IR-R304B High Accuracy and Absorbability Western Blot Detection Kit 50Assays


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