ACE1 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB;IHC
| Verified Samples |
Verified Samples in WB:Human ileum adenocarcinoma,Human testis,Human prostate Verified Samples in IHC:Human breast cancer,Human lung cancer |
| Dilution | WB 1:200-1:1000;IHC 1:100-1:300 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthetic peptide of human ACE |
| Abbre | ACE |
| Synonyms | ACE 1;ACE;ACE T;ACE;ACE1;Angiotensin converting enzyme somatic isoform;Angiotensin converting enzyme testis specific isoform;Angiotensin I converting enzyme 1;Angiotensin I converting enzyme;Angiotensin I converting enzyme peptidyl dipeptidase A 1;angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript;Angiotensin-converting enzyme;Carboxycathepsin;CD 143;CD143;CD143 antigen;DCP 1;DCP;DCP1;Dipeptidyl carboxypeptidase 1;Dipeptidyl carboxypeptidase I;Kininase II;MGC26566;MVCD3;Peptidase P;Peptidyl dipeptidase A;soluble form;Testicular ECA抗体 |
| Swissprot | |
| Calculated MW | 150kDa |
| Cellular Localization | Secreted and Cell membrane. |
| Concentration | 0.5 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Cell Biology; Cardiovascular; Metabolism; Signal Transduction; Stem Cells |
| Conjugation | Unconjugated |
| Background | This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. |
Western Blot analysis of Human ileum adenocarcinoma tissue, Human testis and prostate tissue using ACE1 Polyclonal Antibody at dilution of 1:240
Immunohistochemistry of paraffin-embedded Human breast cancer using ACE1 Polyclonal Antibody at dilution of 1:70
Immunohistochemistry of paraffin-embedded Human lung cancer using ACE1 Polyclonal Antibody at dilution of 1:70
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Naringin administration mitigates oxidative stress, anemia, and hypertension in lead acetate-induced cardio-renal dysfunction in cockerel chicks
IF: 5.19Journal：ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH -
Naringin abrogates angiotensin-converting enzyme (ACE) activity and podocin signaling pathway in cobalt chloride-induced nephrotoxicity and hypertension
IF: 2.663Journal：BIOMARKERS
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