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ACTL6B Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse; Rat
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:Hela,HepG2
Verified Samples in IHC:Human esophagus cancer,Human ovarian cancer
Dilution
WB 1:1000-1:5000;IHC 1:50-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human ACTL6B
Abbre
ACTL6B
Synonyms
53 kDa BRG1 associated factor B;53 kDa BRG1-associated factor B;ACL 6B;ACL6B;ACL6B;Actin like 6;Actin like protein 6B;Actin like protein6B;Actin related protein;Actin related protein Baf53b;actin-like 6B;Actin-like protein 6B;Actin-related protein Baf53b;Actl 6;ACTL 6B;Actl6;ACTL6 B;Actl6b;Arp Na;ArpN a;ArpN alpha;ArpNa;ArpNalpha;Baf 53b;BAF53B;BRG1-associated factor 53B抗体
Swissprot
Calculated MW
47 kDa
Observed MW
Refer to figures
Cellular Localization
Nucleus.
Concentration
1.74 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cancer; Epigenetics and Nuclear Signaling; Neuroscience; Stem cells
Conjugation
Unconjugated
Background
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants.
Western blot analysis of Hela and HepG2 cell lysates using ACTL6B Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ACTL6B Polyclonal Antibody at dilution of 1:100(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using ACTL6B Polyclonal Antibody at dilution of 1:100(×200)


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