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ARAP1 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human colon cancer
Dilution
IHC 1:100-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human ARAP1
Abbre
ARAP1
Synonyms
2410002L19Rik;ANK repeat and PH domain-containing protein 1;ARAP 1;Arap1;ARAP1;Arf GAP Rho GAP ankyrin repeat and pleckstrin homology domains containing protein 1;Arf GAP Rho GAP ankyrin repeat and pleckstrin homology domain containing protein 1;Arf-GAP with Rho-GAP domain;CENT D2;Centaurin delta 2;Centaurin delta2;Centaurin-delta-2;CENTD 2;CENTD2;Cnt d2;Cnt-d2;Cntd2;KIAA0782;MGC176140;mKIAA0782
Swissprot
Cellular Localization
Cytoplasm. Golgi apparatus>Golgi stack membrane. Cell membrane. Associated with Golgi stacks in resting cells. Throughout the cytoplasm and in surface protrusion in cells that are in the process of attaching to a surface and spreading.
Concentration
1 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Signal Transduction
Conjugation
Unconjugated
Background
The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using ARAP1 Polyclonal Antibody at dilution 1:80


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