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ASH2L Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human colon cancer,Human thyroid cancer
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human ASH2L
Abbre
ASH2L
Synonyms
ASH 2;Ash2 (absent small or homeotic) like;Ash2 (absent;small;or homeotic) like (Drosophila);ASH2;ASH2 LIKE;ASH2 like protein;ASH2-like protein;Ash2l;ASH2L;ASH2L1>;ASH2L2;Bre 2;Bre2;Discs 2-like;Drosophila absent;small;or homeotic;Drosophila ASH2-like;Set1/Ash2 histone methyltransferase complex subunit ASH2抗体
Swissprot
Cellular Localization
Nucleus.
Concentration
0.4 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Epigenetics and Nuclear Signaling
Conjugation
Unconjugated
Background
The human ASH2L gene encodes a 628 amino acid protein known as ASH2L1, or isoform 1, which contains a nuclear localization signal and PHD finger motif, suggesting that the gene product functions as a transcription regulator. Alternative splicing results in a shorter isoform 2, designated ASH2L2, which is missing the first 94 amino acid residues found in ASH2L1. Human ASH2L proteins are 60% homologous to Drosophila ash2, which positively regulates expression of certain genes in early development, and contain similar, but not identical, domains, including a zinc finger motif. ASH2L is highly expressed in fetal liver, testis and leukemia cell lines with erythroid and megakaryocytic potential, such as K562, Hel and Dami.
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using ASH2L Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ASH2L Polyclonal Antibody at dilution 1:60


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