ATG16L1 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human; Mouse
- 应用性： WB;IHC
| Verified Samples |
Verified Samples in WB:Raji Verified Samples in IHC:Human breast cancer,Human gastric cancer |
| Dilution | WB 1:500-1:2000;IHC 1:30-1:150 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthetic peptide of human ATG16L1 |
| Abbre | ATG16L1 |
| Synonyms | A16L1;APG16 like 1;APG16-like 1;APG16L;APG16L beta;ATG16 autophagy related 16 like 1;ATG16 autophagy related 16-like 1 (S. cerevisiae);ATG16A;ATG16L;Atg16l1;Autophagy related protein 16 1;Autophagy-related protein 16-1;FLJ00045;FLJ10035;FLJ10828;FLJ22677;IBD10;OTTHUMP00000164391;OTTHUMP00000164393;OTTHUMP00000165876;OTTHUMP00000165877;WD repeat domain 30;WDR30抗体 |
| Swissprot | |
| Calculated MW | 68 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytoplasm. Preautophagosomal structure membrane. Recruited to omegasomes membranes by WIPI2. Omegasomes are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures. Localized to preautophagosomal structure (PAS) where it is involved in the membrane targeting of ATG5. Localizes also to discrete punctae along the ciliary axoneme. |
| Concentration | 0.9 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer; Cell Biology; Cardiovascular; Metabolism; Neuroscience; Signal Transduction |
| Conjugation | Unconjugated |
| Background | ATG16L1 (Autophagy Related 16 Like 1) is a Protein Coding gene. Diseases associated with ATG16L1 include Inflammatory Bowel Disease 10 and Inflammatory Bowel Disease. Among its related pathways are Autophagy Pathway and Senescence and Autophagy in Cancer. GO annotations related to this gene include identical protein binding. An important paralog of this gene is ATG16L2.The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene. |
Western blot analysis of Raji cell using ATG16L1 Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using ATG16L1 Polyclonal Antibody at dilution of 1:40(×200)
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ATG16L1 Polyclonal Antibody at dilution of 1:40(×200)
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| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
