BAG2 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human
- 应用性： WB;IHC
| Verified Samples |
Verified Samples in WB:A549,A431,Hela,Jurkat,HepG2 Verified Samples in IHC:Human prostate cancer,Human lung cancer |
| Dilution | WB 1:500-1:2000;IHC 1:20-1:100 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthetic peptide of human BAG2 |
| Abbre | BAG2 |
| Synonyms | BAG 2;BAG family molecular chaperone regulator 2;BAG-2;BAG-family molecular chaperone regulator-2;Bag2;BAG2;BCL 2 associated athanogene 2;Bcl-2-associated athanogene 2;BCL2 associated athanogene 2;BCL2-associated athanogene 2;dJ417I1.2 (BAG family molecular chaperone regulator 2);dJ417I1.2;KIAA0576;MGC149462;OTTHUMP00000016668 |
| Swissprot | |
| Calculated MW | 24 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytoskeleton,Cytoplasm |
| Concentration | 0.8 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Cell Biology;Signal Transduction;Cancer;Metabolism |
| Conjugation | Unconjugated |
| Background | BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
Western blot analysis of A549 A431 Hela Jurkat and HEPG2 cell using BAG2 Polyclonal Antibody at dilution of 1:300
Immunohistochemistry of paraffin-embedded Human prost at e cancer tissue using BAG2 Polyclonal Antibody at dilution of 1:25(×200)
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using BAG2 Polyclonal Antibody at dilution of 1:25(×200)
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
